- Scale up your lab's services with
Comprehensive applications for automated NGS analysis, variant interpretation and reporting
- From NGS data analysis to drug discovery
Accelerating Genetic Research
The Geneyx Applications are “off-the-shelf” products that offer comprehensive coverage for hereditary and somatic gene panels. These products offer researchers rapid insights into their cases with the option to automatically report the results in customizable formats.
Select from numerous tests and reports with a click of a button! No additional set-up is required.
Select from our portfolio of clinical application:
Pharmacogenomics
Carrier Screening
Gene Panels
Pharmacogenomics (PGx) studies the association between genetic variants and drug metabolism and has many advantages for the field of precision medicine. The adoption of PGx in clinical and diagnostic environments is continuing to gain traction as knowledgebases and novel genetic insights continue to improve. Geneyx realizes the importance of this field and, as a result, offers a comprehensive PGx workflow to all users.
PharmacogeneYX -The Geneyx PGx workflow offers comprehensive interpretations for 13 CPIC level A/B and PharmgKB level 1/2 genes that affect the metabolism of 68 commonly prescribed drugs. This information is consolidated from multiple annotation sources, including Clinical Pharmacogenomic Implementation Consortium (CPIC), Food and Drug Administration (FDA), and the Pharmacogenomics Knowledge Base (PharmGKB). For every gene reported there are also useful hyperlinks to these databases, all of which are automatically pulled into the report.
PharmacogeneYX -The Geneyx PGx report includes detailed case and drug information that is easy to comprehend and fully customizable. Genes can be easily excluded from the report if they have low quality or missing SNPs and final modifications to the report can be performed in the report editor if required. In more detail, the automated report will display the gene name, genotype, and the impact of the genetic changes on drug metabolism. This is combined with gene descriptions that explain the gene’s function, its association with drug metabolism, and the effect of gene changes on therapeutic effectiveness.
Together, the PharmacogeneYX workflow gives users powerful insights into potentially adverse drug reactions and metabolic responses by harnessing key databases and unique genetic profiles.
Pre-conception carrier screening has been a widely adopted method over the years to determine a couple’s risk of having an affected child of certain autosomal recessive and X-linked disorders. Improvements in technology and scientific knowledge have expanded carrier screening with greater detection rates of mutations for various populations. This test is most appropriate for individuals who wish to have children to determine their carrier status of disease and determine their pregnancy risk of having an affected child.
The Carrier Screening application analyses well-establish autosomal recessive genes to give insights into carrier status for diseases that are severe and/or debilitating.
Ideally, this test utilizes sequencing data from both partners to identify inherited disease variants of autosomal recessive and X-linked inheritance models.
Geneyx Analysis provides a comprehensive portfolio of reports for a variety of common gene panels. Each gene panel details known or suspected associations with the disease or phenotype using the most relevant literature sources and can be easily modified and customized by the user.
Our comprehensive portfolio of gene panels:
- Bone, Skin, and Connective tissue
- Cancer
- Cardiology
- Epilepsy
- Hematology
- Immunology
- Inborn error of metabolism
- Liver, Kidney, Endo, Gastro
- Neurology
- Monogenic diabetes
- Ophthalmology and Hearing loss
- Pulmonology
- Thrombophilia
- Parkinson
Customized gene panels can also be created upon request and easily integrated into the user’s given workflow.
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